Article
The association of single nucleotide polymorphisms in the 5'-regulatory region of the lumican gene with susceptibility to high myopia in Taiwan.
Molecular vision - 4 Aug 2006
Wang I-Jong, Chiang Ting-Hsuan, Shih Yung-Feng, Hsiao Chuhsing Kate, Lu Shao-Chun, Hou Yi-Chih, Lin Luke Long-Kung
Abstract excerpt
PURPOSE: To study the relationships between single nucleotide polymorphisms (SNPs) of lumican, decorin, and DSPG3 genes and high myopia. METHODS: One hundred and twenty adult patients with high myopia (< -10.0 D) and 137 controls were used to study the relationships between the decorin, lumican, and DSPG genes and high myopia. All subjects were free of ocular diseases, other than myopia, as well as of other...
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