Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

FOG-1-mediated recruitment of NuRD is required for cell lineage re-enforcement during haematopoiesis.

The EMBO journal - 20 Jan 2010

Gao Zhiguang, Huang Zan, Olivey Harold E, Gurbuxani Sandeep, Crispino John D, Svensson Eric C

Abstract excerpt

The transcriptional co-factor Friend of GATA1 (FOG-1) has been shown to interact with subunits of the nucleosome remodelling and histone deacetylase (NuRD) complex through a specific motif located at its N-terminus. To test the importance of FOG-1/NuRD interaction for haematopoiesis in vivo, we generated mice with a mutation that specifically disrupts FOG-1/NuRD interaction (FOG-1(R3K5A)). Homozygous FOG-1(R3K5A)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromatin
Share to Erythroid Cells
Share to Erythropoiesis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to GATA2 Transcription Factor

Share to Granulocytes

Share to Hematopoiesis

Share to Megakaryocytes

Share to Nuclear Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 20010697
DOI: 10.1038/emboj.2009.368
PMCID: PMC2824465

Genes

GATA1
GATA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

FOG-1-mediated recruitment of NuRD is required for cell lineage re-enforcement during haematopoiesis.PMID 20010697Read ↗

Antagonism of FOG-1 and GATA factors in fate choice for the mast cell lineageSemantic proximity Read ↗

Distinct domains of the GATA-1 cofactor FOG-1 differentially influence erythroid versus megakaryocytic maturation.Semantic proximity Read ↗

Cofactor-mediated restriction of GATA-1 chromatin occupancy coordinates lineage-specific gene expression.Semantic proximity Read ↗

Sumoylation regulates interaction of FOG1 with C-terminal-binding protein (CTBP).Semantic proximity Read ↗

Controlling hematopoiesis through sumoylation-dependent regulation of a GATA factor.Semantic proximity Read ↗

FOG-2 mediated recruitment of the NuRD complex regulates cardiomyocyte proliferation during heart development.Semantic proximity Read ↗

Interaction between FOG-1 and the corepressor C-terminal binding protein is dispensable for normal erythropoiesis in vivo.Semantic proximity Read ↗

The N termini of Friend of GATA (FOG) proteins define a novel transcriptional repression motif and a superfamily of transcriptional repressors.Semantic proximity Read ↗

GATA proteins work together with friend of GATA (FOG) and C-terminal binding protein (CTBP) co-regulators to control adipogenesis.Semantic proximity Read ↗

Friend of GATA-1-independent transcriptional repression: a novel mode of GATA-1 function.Semantic proximity Read ↗

Antagonism between C/EBPbeta and FOG in eosinophil lineage commitment of multipotent hematopoietic progenitors.Semantic proximity Read ↗

Role of the GATA-1/FOG-1/NuRD Pathway in the Expression of Human β-Like Globin GenesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.