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Article

Selection of mutations to detect multidrug-resistant Mycobacterium tuberculosis strains in Shanghai, China.

Antimicrobial agents and chemotherapy - 1 Mar 2010

Luo Tao, Zhao Ming, Li Xia, Xu Peng, Gui Xiaohong, Pickerill Sam, DeRiemer Kathryn, Mei Jian, Gao Qian

Abstract excerpt

Novel tools are urgently needed for the rapid, reliable detection of multidrug-resistant (MDR) and extensively drug-resistant (XDR) strains of Mycobacterium tuberculosis. To develop such tools, we need information about the frequency and distribution of the mycobacterial mutations and genotypes that are associated with phenotypic drug resistance. In a population-based study, we sequenced specific genes of M....

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Identifiers

PMID: 20008778
DOI: 10.1128/AAC.00964-09
PMCID: PMC2826000

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