Article
Evaluation of the frequency of mutation genes in multidrug-resistant tuberculosis (MDR-TB) strains in Beijing, China.
Epidemiology and infection - 5 Jan 2021
Liu Y, Sun Y, Zhang X, Zhang Z, Xing Q, Ren W, Yao C, Yu J, Ding B, Wang S, Li C
Abstract excerpt
The aim of this study was to explore the frequency and distribution of gene mutations that are related to isoniazid (INH) and rifampin (RIF)-resistance in the strains of the multidrug-resistant tuberculosis (MDR-TB) Mycobacterium tuberculosis (M.tb) in Beijing, China. In this retrospective study, the genotypes of 173 MDR-TB strains were analysed by spoligotyping. The katG, inhA genes and the promoter region of...
Topics
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- Antitubercular Agents
- Bacterial Proteins
- Beijing
- Catalase
- Drug Resistance, Multiple, Bacterial
- Female
- Genotype
- Humans
- Male
- Middle Aged