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Article

The MIA complex is a conserved and novel dynein regulator essential for normal ciliary motility.

The Journal of cell biology - 15 Apr 2013

Yamamoto Ryosuke, Song Kangkang, Yanagisawa Haru-Aki, Fox Laura, Yagi Toshiki, Wirschell Maureen, Hirono Masafumi, Kamiya Ritsu, Nicastro Daniela, Sale Winfield S

Abstract excerpt

Axonemal dyneins must be precisely regulated and coordinated to produce ordered ciliary/flagellar motility, but how this is achieved is not understood. We analyzed two Chlamydomonas reinhardtii mutants, mia1 and mia2, which display slow swimming and low flagellar beat frequency. We found that the MIA1 and MIA2 genes encode conserved coiled-coil proteins, FAP100 and FAP73, respectively, which form the modifier of...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23569216
DOI: 10.1083/jcb.201211048
PMCID: PMC3628515

Genes

MIA
MIA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The MIA complex is a conserved and novel dynein regulator essential for normal ciliary motility.PMID 23569216Read ↗

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