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Article

The role of NOTCH1 signaling in T-ALL.

Hematology. American Society of Hematology. Education Program - 1 Jan 2009

Ferrando Adolfo A

Abstract excerpt

The identification of activating mutations in NOTCH1 in over 50% of T-cell acute lymphoblastic leukemias (T-ALL) has generated major interest in the elucidation of the mechanisms of transformation downstream of oncogenic NOTCH and in the targeting of the NOTCH signaling pathway in this disease. S...

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Source

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Identifiers

PMID: 20008221
DOI: 10.1182/asheducation-2009.1.353
PMCID: PMC2847371

Genes

NOTCH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20008221-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Notch signaling in T-cell acute lymphoblastic leukemia.Semantic proximity Read ↗

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