Article
An NZW-derived interval on chromosome 7 moderates sialadenitis, but not insulitis in congenic nonobese diabetic mice.
Journal of immunology (Baltimore, Md. : 1950) - 15 Jan 2010
Burt Rachel A, Watkins Laura, Tan Iris K L, Wang Nancy, Quirk Fiona, Mackin Leanne, Morgan Phillip, Zhang Jian-Guo, Berzins Stuart P, Morahan Grant, Brodnicki Thomas C
Abstract excerpt
Autoimmune lymphocytic infiltration of the salivary glands, termed sialadenitis, is a pathologic feature of Sjögren's syndrome (SjS) that is also prominent in nonobese diabetic (NOD) mice. Genetic factors regulate sialadenitis, and a previous (NOD x NZW)F2 study detected linkage to murine chromos...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
