Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Comprehensive follow-up of the first genome-wide association study of multiple sclerosis identifies KIF21B and TMEM39A as susceptibility loci.

Human molecular genetics - 1 Mar 2010

Abstract excerpt

Genome-wide association studies (GWASs) have proven highly effective, identifying hundreds of associations across numerous complex diseases. These studies typically test hundreds of thousands of variations and identify hundreds of potential associations. However, to date, follow-up attempts have generally only concentrated on just the few most significant initial associations, leaving the majority of true...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to Disease Susceptibility
Share to Follow-Up Studies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genome, Human

Share to Genome-Wide Association Study

Share to Kinesins

Share to Membrane Proteins

Share to Multiple Sclerosis

Source

Open in PubMed Open full text

Identifiers

PMID: 20007504
DOI: 10.1093/hmg/ddp542
PMCID: PMC2816610

Genes

KIF21B
TMEM39A

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 21 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Comprehensive follow-up of the first genome-wide association study of multiple sclerosis identifies KIF21B and TMEM39A as susceptibility loci.PMID 20007504Read ↗

Genetic variation in the KIF1B locus influences susceptibility to multiple sclerosis.Semantic proximity Read ↗

Replication of KIF21B as a susceptibility locus for multiple sclerosis.Semantic proximity Read ↗

A review of genome-wide association studies for multiple sclerosis: classical and hypothesis-driven approaches.Semantic proximity Read ↗

Common variants at CD40 and other loci confer risk of rheumatoid arthritis.Semantic proximity Read ↗

Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis.Semantic proximity Read ↗

Association of common variants in KIF21B and ankylosing spondylitis in a Chinese Han population: a replication study.Semantic proximity Read ↗

Genome‐wide association studies of multiple sclerosisSemantic proximity Read ↗

Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20.Semantic proximity Read ↗

Genome-wide association study of multiple sclerosis confirms a novel locus at 5p13.1.Semantic proximity Read ↗

The autoimmune disease-associated KIF5A, CD226 and SH2B3 gene variants confer susceptibility for multiple sclerosis.Semantic proximity Read ↗

Identification of a novel risk locus for multiple sclerosis at 13q31.3 by a pooled genome-wide scan of 500,000 single nucleotide polymorphisms.Semantic proximity Read ↗

Genome-wide association studies in multiple sclerosis: lessons and future prospects.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.