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Article

Genetic variation in the KIF1B locus influences susceptibility to multiple sclerosis.

Nature genetics - 1 Dec 2008

Aulchenko Yurii S, Hoppenbrouwers Ilse A, Ramagopalan Sreeram V, Broer Linda, Jafari Naghmeh, Hillert Jan, Link Jenny, Lundström Wangko, Greiner Eva, Dessa Sadovnick A, Goossens Dirk, Van Broeckhoven Christine, Del-Favero Jurgen, Ebers George C, Oostra Ben A, van Duijn Cornelia M, Hintzen Rogier Q

Abstract excerpt

The few loci associated with multiple sclerosis (MS) are all related to immune function. We report a GWA study identifying a new locus replicated in 2,679 cases and 3,125 controls. An rs10492972[C] variant located in the KIF1B gene was associated with MS with an odds ratio of 1.35 (P = 2.5 x 10(-...

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Identifiers

PMID: 18997785
DOI: 10.1038/ng.251

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-18997785-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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