Article
Genome-wide association study of multiple sclerosis confirms a novel locus at 5p13.1.
PloS one - 1 Jan 2012
Matesanz Fuencisla, González-Pérez Antonio, Lucas Miguel, Sanna Serena, Gayán Javier, Urcelay Elena, Zara Ilenia, Pitzalis Maristella, Cavanillas María L, Arroyo Rafael, Zoledziewska Magdalena, Marrosu Marisa, Fernández Oscar, Leyva Laura, Alcina Antonio, Fedetz Maria, Moreno-Rey Concha, Velasco Juan, Real Luis M, Ruiz-Peña Juan Luis, Cucca Francesco, Ruiz Agustín, Izquierdo Guillermo
Abstract excerpt
Multiple Sclerosis (MS) is the most common progressive and disabling neurological condition affecting young adults in the world today. From a genetic point of view, MS is a complex disorder resulting from the combination of genetic and non-genetic factors. We aimed to identify previously unidentified loci conducting a new GWAS of Multiple Sclerosis (MS) in a sample of 296 MS cases and 801 controls from the...
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