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Article

5,7‐Dimethoxyflavone, an activator of PPARα/γ, inhibits UVB‐induced MMP expression in human skin fibroblast cells

20 Dec 2011

Abstract excerpt

Peroxisome proliferator-activated receptors (PPARs), which are members of the nuclear hormone receptor superfamily, are a family of ligand-activated transcription factors that consist of three isotypes (PPAR α, δ and γ). PPAR activity was previously thought to be limited to lipid metabolism and glucose homeostasis; however, intensive studies of PPARα/γ in recent years have revealed their importance in age-related...

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PMID: 22379967
DOI: 10.1111/j.1600-0625.2011.01435.x

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