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Article

Activation of PPARbeta/delta causes a psoriasis-like skin disease in vivo.

PloS one - 16 Mar 2010

Romanowska Malgorzata, Reilly Louise, Palmer Colin N A, Gustafsson Mattias C U, Foerster John

Abstract excerpt

BACKGROUND: Psoriasis is one of the most frequent skin diseases world-wide. The disease impacts enormously on affected patients and poses a huge financial burden on health care providers. Several lines of evidence suggest that the nuclear hormone receptor peroxisome proliferator activator (PPAR) beta/delta, known to regulate epithelial differentiation and wound healing, contributes to psoriasis pathogenesis. It...

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Source

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Identifiers

PMID: 20300524
DOI: 10.1371/journal.pone.0009701
PMCID: PMC2838790

Genes

STAT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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