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Article

A potential regulatory single nucleotide polymorphism in the promoter of the Klotho gene may be associated with essential hypertension in the Chinese Han population.

Clinica chimica acta; international journal of clinical chemistry - 1 Mar 2010

Wang Hu-Lin, Xu Qiang, Wang Zhang, Zhang Yi-Hua, Si Liang-Yi, Li Xue-Jun, Yang Qi-Hong, Xiao Hang

Abstract excerpt

BACKGROUND: Mice with defects in the Klotho gene exhibit multiple aging phenotypes including arteriosclerosis. We hypothesised that the G-395A polymorphism in the promoter region of the human Klotho gene may contribute to the prevalence of Essential Hypertension (EH). METHODS: We investigate whet...

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Identifiers

PMID: 20005218
DOI: 10.1016/j.cca.2009.12.004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20005218-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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A potential regulatory single nucleotide polymorphism in the promoter of the Klotho gene may be associated with essential hypertension in the Chinese Han population.PMID 20005218Read ↗

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