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Article

The differential effects of age on the association of KLOTHO gene polymorphisms with coronary artery disease.

Metabolism: clinical and experimental - 1 Oct 2006

Rhee Eun-Jung, Oh Ki-Won, Lee Won-Young, Kim Se-Yeon, Jung Chan-Hee, Kim Byung-Jin, Sung Ki-Chul, Kim Bum-Su, Kang Jin-Ho, Lee Man-Ho, Kim Sun-Woo, Park Jung-Roe

Abstract excerpt

The Klotho knockout mouse is thought to be a good animal model for human aging. Recent studies have reported on the association of KLOTHO gene mutation with cardiovascular disease in humans. We observed the frequencies of single nucleotide polymorphisms, that is, G-395A in the promoter region, C1...

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Source

Identifiers

PMID: 16979405
DOI: 10.1016/j.metabol.2006.05.020

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CAD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16979405-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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The differential effects of age on the association of KLOTHO gene polymorphisms with coronary artery disease.PMID 16979405Read ↗

Klotho gene polymorphism may be a genetic risk factor for atherosclerotic coronary artery disease but not for vasospastic angina in Japanese.Semantic proximity Read ↗

KLOTHO gene polymorphism is associated with coronary artery stenosis but not with coronary calcification in a Korean population.Semantic proximity Read ↗

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A potential regulatory single nucleotide polymorphism in the promoter of the Klotho gene may be associated with essential hypertension in the Chinese Han population.Semantic proximity Read ↗

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KLOTHO gene polymorphisms G-395A and C1818T are associated with lipid and glucose metabolism, bone mineral density and systolic blood pressure in Japanese healthy subjects.Semantic proximity Read ↗

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