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Article

Klotho is a genetic risk factor for ischemic stroke caused by cardioembolism in Korean females.

Neuroscience letters - 30 Oct 2006

Kim Younyoung, Kim Jin-Hyuck, Nam Yu Jin, Kong Minyoung, Kim Yun Joong, Yu Kyung-Ho, Lee Byung-Chul, Lee Chaeyoung

Abstract excerpt

An aging-suppressor gene, klotho, is a candidate factor for vascular disease because its deficiency leads to impaired endothelium-dependent vasodilation and impaired angiogenesis. We investigated the association of polymorphisms in klotho with ischemic stroke. We searched for sequence variants in...

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Identifiers

PMID: 16973281
DOI: 10.1016/j.neulet.2006.08.039

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16973281-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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Klotho is a genetic risk factor for ischemic stroke caused by cardioembolism in Korean females.PMID 16973281Read ↗

Association of the functional KL-VS variant of Klotho gene with early-onset ischemic stroke.Semantic proximity Read ↗

A klotho gene single nucleotide polymorphism is associated with the onset of stroke and plasma klotho concentrationSemantic proximity Read ↗

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The differential effects of age on the association of KLOTHO gene polymorphisms with coronary artery disease.Semantic proximity Read ↗

Relationship between polymorphisms G395A in promoter and C1818T in exon 4 of the KLOTHO gene with glucose metabolism and cardiovascular risk factors in Korean women.Semantic proximity Read ↗

G-395A polymorphism in the promoter region of the KLOTHO gene associates with reduced cognitive impairment among the oldest old.Semantic proximity Read ↗

G-395A polymorphism in the promoter region of the KLOTHO gene and hypertension among elderly (90 years and older) Chinese individuals.Semantic proximity Read ↗

KLOTHO gene polymorphism is associated with coronary artery stenosis but not with coronary calcification in a Korean population.Semantic proximity Read ↗

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The Klotho gene G-395A polymorphism and metabolic syndrome in very elderly people.Semantic proximity Read ↗

Association of exonic variants of Klotho with metabolic syndrome in Asian Indians.Semantic proximity Read ↗

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