Article
Early behavioural markers of disease in P301S tau transgenic mice.
Behavioural brain research - 17 Mar 2010
Scattoni Maria Luisa, Gasparini Laura, Alleva Enrico, Goedert Michel, Calamandrei Gemma, Spillantini Maria Grazia
Abstract excerpt
The present study aimed at characterizing the early behavioural changes preceding the onset of disease in a transgenic mouse model of tauopathy. Mice transgenic for human P301S tau protein exhibit many characteristics of human tauopathies, including neurodegeneration, the formation of neuronal ta...
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