Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Targeting the transforming growth factor-β signaling pathway in human cancer

10 Dec 2009

Abstract excerpt

The transforming growth factor-ss (TGF-beta) signaling pathway plays a pivotal role in diverse cellular processes. TGF-beta switches its role from a tumor suppressor in normal or dysplastic cells to a tumor promoter in advanced cancers. It is widely believed that the Smad-dependent pathway is involved in TGF-beta tumor-suppressive functions, whereas activation of Smad-independent pathways, coupled with the loss...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Metabolism, Diabetes, and Cancer
Share to Pancreatic and Hepatic Oncology Research
Share to TGF-β signaling in diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 20001556
DOI: 10.1517/13543780903382609

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Targeting the transforming growth factor-β signaling pathway in human cancerPMID 20001556Read ↗

Exploring TGF-β Signaling in Cancer Progression: Prospects and Therapeutic StrategiesSemantic proximity Read ↗

Transforming growth factor β signaling pathway: A promising therapeutic target for cancerSemantic proximity Read ↗

Role of Transforming Growth Factor Beta in Human CancerSemantic proximity Read ↗

Actions of TGF-beta as tumor suppressor and pro-metastatic factor in human cancer.Semantic proximity Read ↗

Transforming growth factor‐β signaling: Tumorigenesis and targeting for cancer therapySemantic proximity Read ↗

TGF-β signaling in cancerSemantic proximity Read ↗

Molecular Pathways: Targeting the TGF-β Pathway for Cancer TherapySemantic proximity Read ↗

The Dual Role of TGFβ in Human Cancer: From Tumor Suppression to Cancer MetastasisSemantic proximity Read ↗

TGF-β Signaling in Cancer: Mechanisms of Progression and Therapeutic TargetsSemantic proximity Read ↗

Transforming growth factor-beta signaling in cancer.Semantic proximity Read ↗

TGF-β signalling and its role in cancer progression and metastasis.Semantic proximity Read ↗

TGF-β Family Signaling in Tumor Suppression and Cancer Progression.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.