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Article

Progressive spatial processing deficits in a mouse model of the fragile X premutation.

Behavioral neuroscience - 1 Dec 2009

Hunsaker Michael R, Wenzel H Jürgen, Willemsen Rob, Berman Robert F

Abstract excerpt

Fragile X associated tremor/ataxia syndrome (FXTAS) is a neurodegenerative disorder that is the result of a CGG trinucleotide repeat expansion in the range of 55-200 in the 5' UTR of the FMR1 gene. To better understand the progression of this disorder, a knock-in (CGG KI) mouse was developed by substituting the mouse CGG8 trinucleotide repeat with an expanded CGG98 repeat from human origin. It has been shown that...

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Source

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Identifiers

PMID: 20001115
DOI: 10.1037/a0017616
PMCID: PMC3410547

Genes

FMR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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