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Article

Spatiotemporal processing deficits in female CGG KI mice modeling the fragile X premutation.

Behavioural brain research - 15 Jul 2012

Borthwell Rachel M, Hunsaker Michael R, Willemsen Rob, Berman Robert F

Abstract excerpt

The fragile X premutation is a tandem CGG trinucleotide repeat expansion in the fragile X mental retardation 1 (FMR1) gene between 55 and 200 repeats in length. A CGG knock-in (CGG KI) mouse has been developed that models the neuropathology and cognitive deficits reported in fragile X premutation carriers. It has been suggested that carriers of the premutation demonstrate a spatiotemporal hypergranularity, or...

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Share to Exploratory Behavior
Share to Fragile X Mental Retardation Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22561129
DOI: 10.1016/j.bbr.2012.04.029
PMCID: PMC3378809

Genes

FMR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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