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Article

Narrowing the boundaries of the genetic architecture of schizophrenia.

Schizophrenia bulletin - 1 Jan 2010

Wray Naomi R, Visscher Peter M

Abstract excerpt

Genetic architecture of a disease comprises the number, frequency, and effect sizes of genetic risk alleles and the way in which they combine together. Before the genomic revolution, the only clue to underlying genetic architecture of schizophrenia came from the recurrence risks to relatives and the segregation patterns within families. From these clues, very simple genetic architectures could be rejected, but...

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Identifiers

PMID: 19996148
DOI: 10.1093/schbul/sbp137
PMCID: PMC2800151

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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