Article
Schizophrenia genomics: genetic complexity and functional insights.
Nature reviews. Neuroscience - 1 Sept 2024
Sullivan Patrick F, Yao Shuyang, Hjerling-Leffler Jens
Abstract excerpt
Determining the causes of schizophrenia has been a notoriously intractable problem, resistant to a multitude of investigative approaches over centuries. In recent decades, genomic studies have delivered hundreds of robust findings that implicate nearly 300 common genetic variants (via genome-wide association studies) and more than 20 rare variants (via whole-exome sequencing and copy number variant studies) as...
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