Article

How variation in risk allele output and gene interactions shape the genetic architecture of schizophrenia

2022-03-07

Abstract excerpt

<title>Abstract</title> <p>Schizophrenia is a highly heritable polygenic psychiatric disorder. Characterization of its genetic architecture may lead to a better understanding of the overall burden of risk variants and how they determine susceptibility to disease. A major goal of this project was to develop a modeling approach to compare and quantify the relative effects of single nucleotide polymorphisms (SNPs),...

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Literature Corpus work: 21ee46af-7b01-504d-b214-24f643f88b6d
DOI: 10.21203/rs.3.rs-1420609/v1

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