Article
In pursuit of the high-resolution structure of nicotinic acetylcholine receptors.
The Journal of physiology - 15 Feb 2010
Chen Lin
Abstract excerpt
The nicotinic acetylcholine receptor (nAChR) has been studied extensively for well over four decades because of its important physiological roles and medical relevance. A large body of data from biochemical and biophysical studies are now available. The structural information, which is needed to integrate existing data to address the mechanism and function of nAChRs, started to emerge in recent years. Structural...
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