Article
Rational understanding of nicotinic receptors drug binding.
Current topics in medicinal chemistry - 1 Jan 2004
Grutter Thomas, Le Novère Nicolas, Changeux Jean-Pierre
Abstract excerpt
The atomic determination of the acetylcholine binding protein (AChBP), a molluscan cholinergic protein, homologous to the amino-terminal extracellular domain of nicotinic receptors (nAChRs), offers opportunities for the modeling of the acetylcholine binding site and its ligands. Recently, we cons...
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