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Article

Shared genetic risk contributes to type 1 and type 2 diabetes etiology

6 Nov 2018

Abstract excerpt

The extent to which shared genetic risk contributes to T1D and T2D etiology is unknown. In this study, we generated T1D association data of 15k samples imputed into the HRC panel which we compared to published T2D association data imputed into 1000 Genomes. The effects of genetic variants on T1D and T2D risk at known loci and genome-wide were positively correlated. Increased risk of T1D and T2D was correlated...

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PMID: 30407494
DOI: 10.1093/hmg/ddy314

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