Article
The effects of protein interactions, gene essentiality and regulatory regions on expression variation.
BMC systems biology - 26 Jun 2008
Zhou Linqi, Ma Xiaotu, Sun Fengzhu
Abstract excerpt
BACKGROUND: Identifying factors affecting gene expression variation is a challenging problem in genetics. Previous studies have shown that the presence of TATA box, the number of cis-regulatory elements, gene essentiality, and protein interactions significantly affect gene expression variation. Nonetheless, the need to obtain a more complete understanding of such factors and how their interactions influence gene...
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