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Article

The Orphan Rev-Erb Nuclear Receptors: A Link between Metabolism, Circadian Rhythm and Inflammation?

1 Jan 2006

Abstract excerpt

Nuclear hormone receptors (NRs) function as ligand dependent DNA binding proteins that translate physiological/nutritional signals into gene regulation. Dysfunctional NR signaling leads to many disorders in reproduction, inflammation, and metabolism. The opportunity to identify novel regulatory pathways in the context of human health and disease drives the challenge to unravel the biological function of the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16741567
DOI: 10.1621/nrs.04009

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