Article
Methylenetetrahydrofolate reductase genotype association with the risk of follicular lymphoma.
Cancer genetics and cytogenetics - 1 Dec 2009
Ismail Said I, Ababneh Nida A, Khader Yousef, Abu-Khader Ahmad A, Awidi Abdullah
Abstract excerpt
The metabolism of folate is essential in DNA synthesis, and polymorphisms of genes involved in such metabolism have been implicated in many types of cancer. Among these, the methylene tetrahydrofolate reductase gene (MTHFR) encodes an enzyme that converts folate to a methyl donor used for DNA met...
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