Article
Allele and Genotype Frequencies of the Polymorphic Methylenetetrahydrofolate Reductase and Lung Cancer in ther Jordanian Population: a Case Control Study.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2015
Al-Motassem Yousef, Shomaf Maha, Said Ismail, Berger Sondra, Ababneh Nidaa, Diab Ola, Obeidat Nathir, Awidi Abdallah
Abstract excerpt
BACKGROUND: Methylenetetrahydrofolate reductase (MTHFR) is involved in amino acid synthesis and DNA function. Two common polymorphisms are reported, C677T and A1298C, that are implicated in a number of human diseases, including cancer. OBJECTIVE: The association between MTHFR C677T and A1298C genotype and haplotype frequencies in risk for lung cancer (LC) was investigated in the Jordanian population. MATERIALS...
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