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Article

DNA repair capacity and acute radiotherapy adverse effects in Italian breast cancer patients.

Mutation research - 3 Feb 2010

Sterpone Silvia, Cornetta Tommaso, Padua Luca, Mastellone Valeria, Giammarino Daniela, Testa Antonella, Tirindelli Donatella, Cozzi Renata, Donato Vittorio

Abstract excerpt

Therapeutic exposure to ionising radiation can induce normal tissue side effects which consistently differ among individuals suggesting a possible genetic control. One approach to elucidate the underlying mechanisms is to analyse the relation between genetic traits, biomarkers of in vitro DNA damage and side toxicity in vivo. 43 breast cancer (BC) patients receiving radiotherapy after a breast-conserving surgery...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to X-ray Repair Cross Complementing Protein 1

Source

Identifiers

PMID: 19962393
DOI: 10.1016/j.mrfmmm.2009.11.009

Genes

XRCC1
OGG1
XRCC3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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