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Article

Association between DNA damage, DNA repair genes variability and clinical characteristics in breast cancer patients.

Mutation research - 15 Dec 2008

Synowiec Ewelina, Stefanska Joanna, Morawiec Zbigniew, Blasiak Janusz, Wozniak Katarzyna

Abstract excerpt

The cell's susceptibility to DNA damage and its ability to repair this damage are important for cancer induction, promotion and progression. In the present work we determined the level of basal (total endogenous) and endogenous oxidative DNA damage as well as polymorphism of the DNA repair genes: RAD51 (135 G/C), XRCC3 (Thr241Met), OGG1 (Ser326Cys) and XPD (Lys751Gln) in peripheral blood lymphocytes of 41 breast...

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Source

Identifiers

PMID: 18977234
DOI: 10.1016/j.mrfmmm.2008.09.014

Genes

RAD51
OGG1
XRCC3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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