Article
Genetic polymorphisms in XRCC1, OGG1, and XRCC3 DNA repair genes and DNA damage in radiotherapy workers.
Environmental science and pollution research international - 1 Dec 2020
Soliman Asmaa H M, Zaki Nasef N, Fathy Hala M, Mohamed Aml A, Ezzat Mohamed A, Rayan Amal
Abstract excerpt
DNA damage may develop at any dose of ionizing radiation. DNA damage activates pathways that regulate cell growth and division or coordinate its replication and repair. The repair pathways, base excision repair (BER) and single-strand break repair (SSBR), can repair such damages efficiently and maintain genome integrity. Loss of this repair process or alteration of its control will be associated with serious...
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