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Article

Genetic factors in individual radiation sensitivity.

DNA repair - 1 Apr 2014

Hornhardt Sabine, Rößler Ute, Sauter Wiebke, Rosenberger Albert, Illig Thomas, Bickeböller Heike, Wichmann Hans-Erich, Gomolka Maria

Abstract excerpt

Cancer risk and radiation sensitivity are often associated with alterations in DNA repair, cell cycle, or apoptotic pathways. Interindividual variability in mutagen or radiation sensitivity and in cancer susceptibility may also be traced back to polymorphisms of genes affecting e.g. DNA repair capacity. We studied possible associations between 70 polymorphisms of 12 DNA repair genes with basal and initial DNA...

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Identifiers

PMID: 24674628
DOI: 10.1016/j.dnarep.2014.02.001

Genes

ATM
RAD50
XRCC1
MRE11
MSH2
XRCC4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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