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Article

Design, synthesis and evaluation of high-affinity binders for the celiac disease associated HLA-DQ2 molecule.

Molecular immunology - 1 Feb 2010

Kapoerchan Varsha V, Wiesner Martina, Hillaert Ulrik, Drijfhout Jan W, Overhand Mark, Alard Philippe, van der Marel Gijs A, Overkleeft Hermen S, Koning Frits

Abstract excerpt

Celiac disease is caused by uncontrolled CD4 T-cell responses directed to wheat-derived gluten peptides bound to the disease predisposing HLA-DQ molecules. The only available treatment is a life-long gluten-free diet which is complicated by the widespread use of wheat-derived gluten in the food i...

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Source

Identifiers

PMID: 19962195
DOI: 10.1016/j.molimm.2009.10.036

Genes

ADA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-19962195-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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