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Article

A pooling-based genome-wide analysis identifies new potential candidate genes for atopy in the European Community Respiratory Health Survey (ECRHS).

BMC medical genetics - 6 Dec 2009

Castro-Giner Francesc, Bustamante Mariona, Ramon González Juan, Kogevinas Manolis, Jarvis Deborah, Heinrich Joachim, Antó Josep-Maria, Wjst Matthias, Estivill Xavier, de Cid Rafael

Abstract excerpt

BACKGROUND: Asthma and atopy are complex phenotypes with shared genetic component. In this study we attempt to identify genes related to these traits performing a two-stage DNA pooling genome-wide analysis in order to reduce costs. First, we assessed all markers in a subset of subjects using DNA pooling, and in a second stage we evaluated the most promising markers at an individual level. METHODS: For the...

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Identifiers

PMID: 19961619
DOI: 10.1186/1471-2350-10-128
PMCID: PMC2797505

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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