Article
Pooled genome-wide analysis to identify novel risk loci for pediatric allergic asthma.
PloS one - 16 Feb 2011
Ricci Giampaolo, Astolfi Annalisa, Remondini Daniel, Cipriani Francesca, Formica Serena, Dondi Arianna, Pession Andrea
Abstract excerpt
BACKGROUND: Genome-wide association studies of pooled DNA samples were shown to be a valuable tool to identify candidate SNPs associated to a phenotype. No such study was up to now applied to childhood allergic asthma, even if the very high complexity of asthma genetics is an appropriate field to explore the potential of pooled GWAS approach. METHODOLOGY/PRINCIPAL FINDINGS: We performed a pooled GWAS and...
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