Article
Prevalence of IGFBP3, NOS3 and TCF7L2 polymorphisms and their association with hypertension: a population-based study with Brazilian women of African descent.
BMC research notes - 17 May 2021
Neto Abel Barbosa Lira, Vasconcelos Nancy Borges Rodrigues, Dos Santos Tamara Rodrigues, Duarte Luisa Elvira Cavazzani, Assunção Monica Lopes, de Sales-Marques Carolinne, Ferreira Haroldo da Silva
Abstract excerpt
OBJECTIVE: African ancestry seems to be a risk factor for hypertension; however, few genetic studies have addressed this issue. This study aimed to investigate the prevalence of polymorphisms NOS3; rs1799983, IGFBP3; rs11977526 and TCF7L2; rs7903146 in Brazilian women of African descent and their association with hypertension. RESULTS: The prevalences of the less frequent genotypes were 26.5% TT genotype of NOS3;...
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