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Article

Short hairpin RNA targeting beta-catenin suppresses cell proliferation and induces apoptosis in human gastric carcinoma cells.

Scandinavian journal of gastroenterology - 1 Jan 2009

Jiang Hong, Xia Jianguo, Kang Jian, Ding Yongbin, Wu Wenxi

Abstract excerpt

OBJECTIVE: Aberrant activation of Wnt/beta-catenin signaling is involved in various cancers, including human gastric cancer. Here we investigate the role of Wnt/beta-catenin signaling in regulating gastric cancer cell apoptosis. MATERIAL AND METHODS: Expression of beta-catenin was investigated after transfection with beta-catenin short hairpin RNA (shRNA) in gastric cancer cells by Western blotting and...

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Source

Identifiers

PMID: 19958059
DOI: 10.3109/00365520903342166

Genes

AKT2
IRAK1
MALT1
PDCD2
PERP
TNFAIP3
TNFRSF25
TRAF3
YWHAB
YWHAZ

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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