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Article

Gene responsible for deficient activity of the beta subunit of C8, the eighth component of complement, is located on mouse chromosome 4.

Immunogenetics - 1 Jan 1991

Tanaka S, Suzuki T, Sakaizumi M, Harada Y, Matsushima Y, Miyashita N, Fukumori Y, Inai S, Moriwaki K, Yonekawa H

Abstract excerpt

Sera from 73 strains of mice were tested for hemolytic activity through the classical and the alternative pathways (CP and AP) in a single radial hemolysis assay. Sera from 16 out of 45 laboratory inbred strains had no lytic activity, and Ouchterlony analysis with anti-C5 serum showed them to be C5-deficient. Sera from 2 out of 28 strains derived from wild mice also had no lytic activity, but the C5 molecule was...

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PMID: 1995474
DOI: 10.1007/BF00211691

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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