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Article

A simple PCR-based method for the rapid genotyping of inherited fifth complement component (C5)-deficient mice.

Experimental animals - 1 Jan 2015

Wang Qingkai, Wang Na, Zhang Xin, Hu Weiguo

Abstract excerpt

The fifth component of complement (C5) is considered to be the center of complement activation and function. However, there are no genetically engineered knockout mice for this gene, and the only commercially available inherited C5-deficient mice, in which a "TA" nucleotide deletion in the coding frame was previously identified, are in theC57BL/10Sn genetic background rather than the commonly used backgrounds...

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Identifiers

PMID: 25765875
DOI: 10.1538/expanim.14-0085
PMCID: PMC4547999

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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