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Article

Molecular basis for complement component 6 (C6) deficiency in rats and mice.

Immunobiology - 1 Jan 2004

Bhole Deepak, Stahl Gregory L

Abstract excerpt

Complement component C6 is a part of the lytic membrane attack complex formed during complement activation. Animal modeling to define the role of C5a vs. C5b-9 in human disease has used rodents deficient in C6, yet the molecular basis for the deficiencies has not been ascertained. Oligonucleotides derived from a 493 bp EST sequence of the rat C6 gene were used to isolate full-length transcripts of rat C6 mRNA....

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PMID: 15568620
DOI: 10.1016/j.imbio.2004.08.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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