Article
Restriction fragment length polymorphism of the murine C4 and Slp genes: two C4 groups.
Journal of immunology (Baltimore, Md. : 1950) - 1 Nov 1992
Miller R D, Aizawa Y, Shreffler D C
Abstract excerpt
We have examined the related H-2 genes coding for the fourth component of complement (C4) and the sex-limited protein (Slp) from 30 inbred mouse strains by Southern blot analysis. With four restriction enzymes, 11 RFLP patterns distributed among 26 different H-2 haplotypes have been identified. Strains of the same serologic H-2 haplotype were found to have identical RFLP patterns. It was confirmed that the number...
Topics
- Animals
- Blood Proteins
- Blotting, Southern
- Complement C4
- DNA
- DNA Probes
- Genetic Linkage
- Genotype
- Major Histocompatibility Complex
- Mice
- Mice, Inbred Strains
- Molecular Sequence Data