Article
miRNA processing turned upside down.
The EMBO journal - 2 Dec 2009
Schwab Rebecca, Voinnet Olivier
Abstract excerpt
MicroRNAs are 19-22 nt-long RNAs that regulate eukaryotic gene expression. They are processed from stem-loop containing precursor transcripts by RNAse III enzymes of the Dicer family. In this issue of the EMBO Journal, a study by Bologna and colleagues investigates the processing of two plant MIRNA families with unusually long precursors. Their findings suggest a non-canonical mode of biogenesis in which DCL1,...
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