Article
RNA secondary structural determinants of miRNA precursor processing in Arabidopsis.
Current biology : CB - 12 Jan 2010
Song Liang, Axtell Michael J, Fedoroff Nina V
Abstract excerpt
MicroRNAs (miRNAs) are excised from hairpin structures within primary miRNAs (pri-miRNAs). Most animal pri-miRNAs are processed by two cleavages, the first at a loop-distal site approximately 11 nucleotides (nt) from the end of the hairpin and the second approximately 22 nt beyond the first. To i...
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