Article
Identification of key sequence features required for microRNA biogenesis in plants.
Nature communications - 21 Oct 2020
Rojas Arantxa M L, Drusin Salvador I, Chorostecki Uciel, Mateos Julieta L, Moro Belén, Bologna Nicolas G, Bresso Edgardo G, Schapire Arnaldo, Rasia Rodolfo M, Moreno Diego M, Palatnik Javier F
Abstract excerpt
MicroRNAs (miRNAs) are endogenous small RNAs of ∼21 nt that regulate multiple biological pathways in multicellular organisms. They derive from longer transcripts that harbor an imperfect stem-loop structure. In plants, the ribonuclease type III DICER-LIKE1 assisted by accessory proteins cleaves the precursor to release the mature miRNA. Numerous studies highlight the role of the precursor secondary structure...
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