Article
Estimating population genetic parameters and comparing model goodness-of-fit using DNA sequences with error.
Genome research - 1 Jan 2010
Liu Xiaoming, Fu Yun-Xin, Maxwell Taylor J, Boerwinkle Eric
Abstract excerpt
It is known that sequencing error can bias estimation of evolutionary or population genetic parameters. This problem is more prominent in deep resequencing studies because of their large sample size n, and a higher probability of error at each nucleotide site. We propose a new method based on the...
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