Article
Estimating effective population size or mutation rate using the frequencies of mutations of various classes in a sample of DNA sequences.
Genetics - 1 Dec 1994
Fu Y X
Abstract excerpt
Mutations resulting in segregating sites of a sample of DNA sequences can be classified by size and type and the frequencies of mutations of different sizes and types can be inferred from the sample. A framework for estimating the essential parameter theta = 4Nu utilizing the frequencies of mutations of various sizes and types is developed in this paper, where N is the effective size of a population and mu is...
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