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A Putative P-Type ATPase, Apt1, Is Involved in Stress Tolerance and Virulence in <i>Cryptococcus neoformans</i>

1 Dec 2009

Abstract excerpt

The export of virulence factors, such as the capsule polysaccharide, to the cell surface is a critical aspect of the pathogenicity of Cryptococcus neoformans. A view of capsule export via exocytosis and extracellular vesicles is emerging, but the molecular mechanisms underlying virulence factor transport pathways remain to be established. In this study, we characterized the APT1 gene, which encodes a predicted...

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PMID: 19949048
DOI: 10.1128/ec.00289-09

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