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Article

Prognostic Relevance of Gene Amplifications and Coamplifications in Breast Cancer

1 Dec 2004

Abstract excerpt

Multiple different oncogenes have been described previously to be amplified in breast cancer including HER2, EGFR, MYC, CCND1, and MDM2. Gene amplification results in oncogene overexpression but may also serve as an indicator of genomic instability. As such, presence of one or several gene amplifications may have prognostic significance. To assess the prognostic importance of amplifications and coamplifications...

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Identifiers

PMID: 15574759
DOI: 10.1158/0008-5472.can-04-1945

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