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Article

Evidence for ADAR-induced hypermutation of the Drosophila sigma virus (Rhabdoviridae).

BMC genetics - 26 Nov 2009

Carpenter Jennifer A, Keegan Liam P, Wilfert Lena, O'Connell Mary A, Jiggins Francis M

Abstract excerpt

BACKGROUND: ADARs are RNA editing enzymes that target double stranded RNA and convert adenosine to inosine, which is read by translation machinery as if it were guanosine. Aside from their role in generating protein diversity in the central nervous system, ADARs have been implicated in the hypermutation of some RNA viruses, although why this hypermutation occurs is not well understood. RESULTS: Here we describe...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19941656
DOI: 10.1186/1471-2156-10-75
PMCID: PMC2790459

Genes

ADAR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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